Covid ‘perfect storm’ hit more patients due to more fungal infections | Infectious disease

A The alarm bells have rung in India in the past month following the outbreak of an unusual “black fungus” infection that has infected thousands of critically ill cowardly patients. Scientists are now warning that other dangerous or even deadly fungal infections have been found in critically ill coronavirus patients worldwide, including in the UK.

Fungi are everywhere – in soil, water, air, faeces and human skin. In general, people’s broad, adaptive immune systems are sufficient for a disturbing, but when this shield is weakened by disease, congenital conditions, or age, they are at greater risk of microscopic attack. ۔

When Covid 19 came out, doctors found that the best tools in their arsenal to fight the virus were steroids, which are immunosuppressants. Beware of secondary bacterial infections in intensive care units, doctors often gave corona virus patients broad-spectrum antibiotics as a precaution.

But the combination of the lungs of both good and bad bacteria, which is eliminated by covid, a weakened immune system, and antibiotics, leaves critically ill patients with molds and spears.

“It’s an unfortunate hurricane for these organisms, and we’re seeing it,” said Dr. Tom Chiller, head of the mitochondrial disease branch of the US-based Centers for Disease Control and Prevention (CDC).

Even before the epidemic, an estimate was made about the rates of rare and deadly “black fungus” mucormycosis infections in India. 70 times more than the rest of the world. With Cowade, a recent epidemic, part of which involves liberal steroid use in hospitals and a high proportion of patients with uncontrolled diabetes.

Scientists are now reporting reports of other fungal infections, including pathogens Aspergillus And Candida iris, Hospitalized covid patients have emerged. In particular, the common fungal infection aspergillosis, which is often seen in conjunction with the flu, is seen globally in severe mountain patients, United States United Kingdom , France, Pakistan And India.

A doctor examines a cowardly patient before surgery to remove mucus or black fungus at a hospital in Ghaziabad, India, earlier this month.
A doctor examines a cowardly patient before surgery to remove mucus or black fungus at a hospital in Ghaziabad, India, earlier this month. Photo: Anadolu Agency / Getty Images

A recent meta-review of a study of covid patients admitted to 19 observational hospitals in different countries showed that there were cumulative incidences of covid-related pulmonary aspergluse. 13.5 From 1,421 patients, ranging from 2.5% to 35%. Despite widespread use of antifungals, half of those infected died.

“Basically, the more damage a virus causes to the lungs, the more likely you are to have a fungal infection,” said Dr Darus Armstrong James, a senior clinical lecturer in respiratory fungal diseases at Imperial College London. And the problem with fungal infections is that they are far more deadly than bacterial infections. They are difficult to treat, difficult to diagnose and cause many deaths.

ARMSTRONG – James, who also heads the fungal disease unit at Royal Bromton Hospital, estimates that 10 to 15 per cent of safe cowardly patients have contracted aspergillosis in UK hospitals, based on their own Do it as a therapist.

David Danning, professor of infectious diseases and global health at the University of Manchester, said it contains fluids from the lungs because it contains fluids from the lungs.

“Some people will not want to take this fluid, because it is dangerous [virus that causes] Covid شامل Interacting in the intensive care unit and influencing the people performing the procedure. Feeling hesitant to diagnose.

He said, “Mycorrhiza is very visible … Patients look horrible, they have these dark areas on their face, they are losing their eyesight … it requires major time surgery, That sounds awful. ” “Aspergillosis patients are only sick on the ventilator, and they already have a serious lung disease with covid. And if they die again, it’s all attributed to covid.

He added that given these barriers, the low number of cases of aspergillosis was “extremely likely”. He said the incidence of infections in hospitalized cohort patients was quite reasonable, as doctors could justify regular use of antibiotics for antifungal treatment. Research is underway to assess the feasibility of this approach.

According to Chiller, about half of all people who suffer from mucormycosis die – and aspergillosis can be just as deadly, especially in intensive care patients with covid. “The important thing is to think about the fungus,” he said. “If you don’t think so, you’re not diagnosing it, you’re not treating it, you’re not saving your life.” ۔ “

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