Global immunization: Low-income countries rush to reach vaccine supply | World news

T.Victorious scenes are being presented here as lorries are leaving a vaccine plant in the Indian city of Pune, which will prevent thousands of deaths from loaded boxes. Adar Poonawala, owner and chief executive of the Serum Institute of India, stands on the side of a truck that portrays most of his company’s “proud and historic” moment as a potential savior of the nation – and even A big part of it is the world

Poonawala’s factory, the world’s largest vaccine complex, is the best hope for immunizations for people in Africa and some low-income countries – which could save them from the ravages of the corona virus epidemic. The Serum Institute has been contracted to provide the UN-backed Covacs initiative, which subsidizes low-income countries, including 200 million doses of Covid.

For a heartbreaking moment last week, it seemed that vaccine nationalism was a slap in the face inside India. On January 4, shortly after receiving approval from the Indian regulator by the Serum Institute for a vaccine to be made under the license from Aster Zenica – Poonawala was informed that there was a condition attached to it. The reason was that till then only India could get the vaccine.

Map of factories where the Oxford vaccine will be made

The next day, he described the “confusion in public circles” on Twitter, saying “all countries are allowed to export vaccines.”

But lorries are now heading all over India and tensions have been raised in the incident as every cash-strapped country is taking part in the vaccine battle, putting unprecedented pressure on manufacturers to deliver them.

Because nutritious Europe and North America determine the vaccine to be purchased in advance. Amid allegations that immunization programs are too slow and the wrong people are getting jaw-dropping – not a single shot has been fired in other countries.

Three vaccines have been approved in the West. Pfizer / Biotech and Modern are expensive and require long-term storage at -70C. Pfizer offered to sell the vaccine to South Africa at a 50% discount for ڈالر 10, but said the price was still taboo.

But the Oxford / AstraZeneca vaccine is stable at 2-8C refrigerated temperatures and the AstraZeneca epidemic promises not to be profitable for the duration of the epidemic. It aims to deliver 3bn meals this year, made under license in factories around the world. This is the core of the CoVX initiative, which has purchased a total of 1.97bn dose of four different vaccines for distribution once available. Most of the strain vaccine is for this.

The Serum Institute has promised to make 100 million doses of the Avestar Zenica vaccine for Covacs and another 100 million doses of Novaxis jaws. Kovacs has the option of 900m doses of these vaccines in one or the other.

A spokesman for Gavi, a partner vaccine partner in Quix, said delivery could begin as early as February.

“We expect that in the first half of 2021, each participating economy will be able to protect about 3% of the population. This process could begin by early February, resulting in better regulatory outcomes and better health preparation.” Systems and national regulatory systems in individual participating economies.

“Which countries, as well as which vaccines will be implemented over time, we hope to get more involved soon.”

Seven countries have now granted emergency clearance to the Oxford / AstraZeneca vaccine or Serum Institute version: the United Kingdom, India, Argentina, the Dominican Republic, El Salvador, Mexico and Morocco. AstraZeneca has licensed the Carlos Slim Foundation in Mexico to supply 150 million meals to Latin America. These countries can now ship.

But without a regulatory body, other countries will be waiting to give the green light to the World Health Organization, which is said to need Serum Institute data. The Director-General, Tedros Azanom Ghibrius, said on January 11 that he “hopes to submit a complete dataset to the Serum Institute of India for rapid review so that anyone can determine whether we are of international use.” “They can recommend the AstraZeneca vaccine.”

The AstraZeneca vaccine will also produce S-bioscience in Korea, Bio-Qingtai in China, Siem Biosciences and local collective SCGs in Thailand and CSL variants in Australia. In Brazil, the Ferrous Cruise Institute has signed an agreement with the Serum Institute for 100 million doses of the vaccine, known as “Fill and Finish”.

In an attempt to jump in line, Brazilian President Jair Bolsenaro wrote a letter to Indian Prime Minister Narendra Modi on January 9. Bolsenaro wrote, “In order to implement our national immunization program as soon as possible, we need all possible supplies to be provided to Brazil in Brazil and immediately and threaten the Indian vaccination program of 2 ml of food.” I will compliment them without adding. “

Brazil is now buying 10 million doses of the Russian Sputnik vaccine. The party is late. Late last year, Argentina supplied 300,000 doses and is vaccinating healthcare workers. The Russians claim it is 92% effective, but no figures have been released.

Some middle-income countries have launched immunization programs using Pfizer / Biotech. Mexico delivered 3,000 meals in December. Chile and Costa Rica have also started using the vaccine. Mexican officials have talked to their Argentine counterparts about buying Sputnik.

Chinese vaccines are also being used. Both Bahrain and the United Arab Emirates gave emergency approval to the synophram vaccine in December, which manufacturers say is 86 percent effective, although – unlike the Russian vaccine – full figures have not been released. ۔ Turkey has bought the Chinese vaccine, and Morocco, Egypt and Nigeria have all come under discussion.

Along the way are other intelligent jaws. NovoX aims to make 2bn doses for global use – but has not yet completed its trials. Quax has an option on a 500-meter dose of the Johnson vaccine, which has the advantage of being a shot, but although results from the Phase 3 trial are expected within weeks, it is said to delay manufacturing. However, it can be a big player.

“Johnson & Johnson’s goal is to provide global access to Johnson’s Covid 19 vaccine candidate, if they are safe and effective. “We are committed to developing a bn 1bn vaccine in a year starting in 2021 and have accelerated the manufacturing scale to achieve this goal,” a spokesman said. “We are taking advantage of global supply for our vaccine candidates, including facilities in the United States, Europe, Asia and Africa.”

Even if the amount of vaccines distributed worldwide increases, for all countries, everyone will be able to do so, said David Salisbury, a fellow at Chatham House World Health Program and director of immunizations at the Department of Health until 2013. Will not be able to run vaccination programs. it is needed.

“There is a big difference between the desire to be vaccinated and the political rhetoric that your country will be vaccinated – and in fact the ability to contract in your place or on your behalf and the ability to pay for it – and much more, Ability to implement, “he said.

Vaccination against COVD-19 is not the same as running childhood immunization programs, but more like getting vaccinated against similar seasonal flu. Most low-income countries do not have enough clinics or databases to tell them. How to reach those at risk.

Countries that receive enough vaccines for 20% of the population, which hopes to eventually provide covacs, will not be able to stop the migration. Salisbury said they would be involved in a “never-ending cycle” – health workers and those at risk of death, the elderly and the most vulnerable.

The corona virus is not going away, especially in low-income countries. It can be argued that vaccines are only a temporary cure.

“Predicting the future of vaccine campaigns in all parts of the world is something that many of us are already thinking about. Should it become an annual national vaccination program for industrialized nations?” Until the virus is eradicated, I think the answer is yes, “said Salisbury.” But what about the hunger in low-income countries that are already under a lot of pressure to control the corona virus? , For these resources? Are you hungry? “


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