Immune system of 19 patients may be ready to fight corona virus variants: study

Immune system of 19 patients may be ready to fight corona virus variants: study

NEW YORK (Reuters Health) – People who recover from covid-19 are protected from the novel coronavirus for at least six months and are more likely to live longer, according to a study that found that long-term immunity to infection The system develops and can also block the virulent forms of the virus. Such as the different situation in South Africa.
The research was published in the journal NatureNote that antibodies are produced by immune cells that continue to develop, obviously the remnants of the virus hidden in the intestinal tissues are constantly exposed.
According to scientists, including those from Rockefeller University in the United States, the study provided “the strongest evidence” that the immune system “remembers” the virus and, even after the infection is eliminated, improves the quality of the antibodies. Keeps making
They suspect that when the next recovering patient is exposed to the virus, the response will be faster and more effective in preventing recurrence.
“This is really interesting news,” said Michelle C. Nissenzweig. “We see here that the kind of immune response that could possibly provide protection for some time, is that the body is exposed again.” Enables quick and efficient response from viruses. ” Co-author of the study from Rockefeller University.
While antibodies against coronavirus persist in the blood plasma for several weeks or months, previous research has shown that their levels drop significantly over time.
However, the researchers showed that instead of producing antibodies all the time, the immune system creates memory B cells that recognize the coronavirus, and when it encounters it a second time, it sends a new round of antibodies. Quickly removes.
Because the novel coronavirus mimics the cells in the lungs, upper throat, and small intestine, they suspect that residual virus particles hidden in these tissues could evolve into memory B cells.
In the present study, scientists studied the antibody reactions of 87 people on two occasions – one month after infection, and then six months later.
Although the number of antibodies has decreased significantly despite the detection of antibodies over a six-month period, lab experiments have shown that participants’ plasma samples have a five-fold ability to neutralize the virus. Decreased.
In contrast, the researchers found that the number of patients with memory B cells – especially those who develop antibodies against the coronavirus – did not decrease.
Research has shown that these cells also have a slight increase in some cases.
Scientists also discovered that even after the infection was resolved, several stages of mutation in memory B cells had passed.
As a result, the antibodies they developed were far more effective.
According to the researchers, these antibodies were better able to withstand the virus, and could even recognize a modified version.
“The total number of memory B cells that produced antibodies to the virus attacking the Achilles heel, known as the receptor binding domain, remained the same,” said Christian Gebler, another co-author of the study.
“The good news is that if you have to deal with the virus again, you need them,” said Gebler.

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