Based on two all-India studies on the Kovid-19 virus genome, the Prime Minister’s Office on Saturday confirmed that there is no major mutation of the virus in India. Prime Minister Narendra Modi chaired a meeting on the state of Kovid-19 epidemic and vaccine distribution, distribution and administration.
Earlier, Union Health Minister Harsh Vardhan had said that the Indian Council of Medical Research is doing a large-scale sequencing of nationally representative strains of the SARS-CoV-2 virus collected for several months during different time periods.
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The minister had said that there was no significant or drastic change in strains.
The report states that around 12,000 mutations have been documented in 32 million cases globally. Mutation is the growth that the virus adapts to various barriers.
A recent study has shown that Kovid-19 has a different death rate in different states. An international team led by researchers from Banaras Hindu University (BHU) in Uttar Pradesh analyzed mutations in a gene responsible for the expression of angiotensin converging enzyme 2 (ACE2), a protein on the surface of cells believed to be A gateway to the novel coronavirus in the human body.
Their spatial analysis showed that in India, the frequency of this haplot, or combination of mutations, varied between 33–100 percent in different regions.
The researchers, for the first time, detected a significant positive correlation for the mutation with low infection and case-fatality ratio (CFR) among the Indian population.
“If more people with this haplotype are present in an area, the infectious probability of the virus will be less,” he told the news agency PTI. For example, he notes that state-wise Maharashtra and Gujarat have the lowest frequency of gene mutations at 30–40 percent, while the northeast region has the highest frequency with 75–100 percent gene mutations.
(With PTI inputs)
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