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Permanent immunity against Kovid-19 found after mild or asymptomatic infection: Study – Health

Scientists have found evidence of protective immunity against Kovid-19 in people up to four months after mild or asymptomatic coronovirus infection, providing hope for the long-lasting efficacy of vaccines.

Researchers, including researchers at Queen Mary University in London, analyzed antibody and T cell responses in 136 health workers in the UK who had mild or asymptomatic Kovid-19 infections, dating back to March.

The study, published in a journal called Science Immunology, found that 89 percent of health workers analyzed neutralizing antibodies 16–18 weeks after infection.

The team also includes researchers Imperial College London and University College London, UK, most of the workers had T cells capable of recognizing many different parts of the virus.

However, he noted that the two reactions did not always persist in tact, with some individuals showing T cell immunity, but no evidence of antibodies, and vice versa.

Joseph Gibbons, Queen Mary’s postdoctoral research assistant, said, “SARS-CoV-2 studies in London hospital health workers show that four months after infection, about 90 percent of individuals have antibodies that inhibit the virus. Huh”.

Gibbons said, “Even more encouraging is that in 66 percent of health workers we see that the level of these protective antibodies is high and that strong antibody response is complemented by T cells, which we respond to in different parts of the virus. lets see.”

Describing the discovery as “good news”, he pointed out that if someone has been infected with a coronavirus, there is a good chance that they will have developed antibodies and T cells that provide some protection in the event that the virus is re-encountered. Can.

Much debate over protective immunity focuses on the various roles of B cells, which make antibodies, and T cells, white blood cells that help protect against viruses, including direct killing.

The latest study found that while protective antibody responses were usually complemented by a T cell response, more than half of health workers had various antibody and T cell responses.

Staff did not evoke specific T cell responses to proteins found in the outer layer of the SARS-CoV-2 virus.

The research also found that T cell responses were higher in those with classic, defining symptoms of Kovid-19, while asymptomatic infections had weaker T cell immunity than symptomatic infections, but antibody responses to to equalize.

The new study also gives assurances for vaccination efforts, suggesting that even after mild infection, individuals carry antibodies and T cell immunity to many parts of the virus, known as epitopes.

Researchers noted that when new variants are visible, virus changes do not necessarily occur within these epitopes, so it is expected that the vast majority of immune identities may not exist.

“Our study of asymptomatic and mild cases gives a positive insight into the immunity of SARS-CoV-2 four months after infection,” said Corinna Pade, Queen Mary’s postdoctoral research scientist.

The researchers noted that this is an important finding as none of the symptoms of mild or even Kovid-19 are common and representative of most infections in the community.

“Abundant immune responses also provide hope for the long-lasting efficacy of vaccines,” Ped said.

(This story is published from a wire agency feed without textual modifications.)

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