A Cleveland Clinic study showed that patients who have obesity and who tested positive for Kovid-19 had a previous history of bariatric surgery associated with lower risk of hospitalization and admission to the intensive care unit.
The results were published in the Journal of Obesity and Related Diseases for Surgery.
In the past months, researchers around the world have identified obesity as a risk factor for developing a severe form of Kovid-19, which may require hospital admission, intensive care and use of ventilator support May be required. The Centers for Disease Control and Prevention reported that more than 70% of older adults are overweight or obese, leading to an increased risk of serious illness from coronovirus.
Obesity is a complex disease caused by many factors that weaken the immune system. Obesity creates a chronic inflammatory condition that causes excessive production of cytokines, which are small proteins involved in the immune response.
“Infection with the coronavirus also triggers the immune system to release cytokines, which can lead to excessive cytokine production that damages the organs. This may partially explain the severity of infection in obese patients, ”says Ali Amin, director of the Bariatric and Metabolic Institute at the Cleveland Clinic and principal investigator of the research.
In addition, obesity increases the risk of heart disease, high blood pressure, diabetes, kidney disease and blood clots. Those conditions can lead to poor outcomes after infection with SARS-CoV-2, the virus that causes Kovid-19. Obesity can also affect the respiratory system. Many obese patients have underlying lung conditions, such as sleep apnea and obesity hypoventilation syndrome, which can worsen the results of Kovid-19 pneumonia.
“Dr. Aminian’s study provides further evidence of a significant link between obesity and poor outcomes from coronovirus infection. The study shows for the first time that losing weight through bariatric surgery is actually at risk from a serious disease in these patients May be less, ”says co-author Steven Nissen, MD, Chief Academic Officer of the Heart, officer of the Vascular and Thoracic Institute in Cleveland. Clinic.
Looking at 4,365 patients who tested positive for SARS-CoV-2 between March 8, 2020 and July 22, 2020, the researchers identified 33 patients with a prior history of weight loss surgery (one sleeve in 20 patients Gastrectomy and 13 patients were a Roux-en-Y gastric bypass). At the time of the SARS-CoV-2 trial, 33 surgical patients were matched at 1:10 with the obese patients with obesity to collect a group of 330 control patients with a body mass index of 40 or more.
This matched covalent study of 363 patients showed that weight loss in the bariatric surgical group and improvement in diabetes and hypertension before contracting Kovid-19 was associated with a much lower rate of admission to hospital and ICU.
Eighteen percent of the patients in the weight-loss surgery group and 42% of the patients in the control group required hospitalization after contracting Kovid-19. In addition, 13% of patients in the control group died of ICU admission, 7% required mechanical ventilation, and 2.4% died. None of these occurred in the surgical group.
“Patients become much healthier after bariatric surgery and can fight the virus better,” Dr. Amnion says. “If confirmed by future studies, it could be added to the long list of health benefits of bariatric surgery, such as diabetes, hypertension, fatty liver disease, sleep apnea and heart attack, stroke, kidney disease, and death. prevention of.”
Another Cleveland Clinic study showed that weight loss surgery in patients with diabetes and obesity reduced the risk of death and heart complications by 40 percent.
(This story is published from a wire agency feed without textual modifications.)
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