Researchers find geodetic variations to be more intense

Researchers find geodetic variations to be more intense

Boston: A new one the study Researchers led by researchers at the Beit Israel Deconis Medical Center (BIDMC) have shed light on the genetic risk factors that make people less likely to develop Covid-19.
Every day thousands of people test positive for the virus, and people are still under suspicion because they do not have mild symptoms and others are seriously ill. According to a new the study The study, published in the New England Journal of Medicine (NEJM), led by Robert E. Jarston, chief of the Cardiovascular Medicine Division at the BBDMC, found that New possibilities for treatment of this disease may open up. .
Different patients with COVID-19 show different symptoms and varying degrees of severity, “said Harvard Medical School professor Madison Gerston.” Pre-existing conditions, especially cardiovascular and metabolic disease, the severity of the disease and the consequences. There are risk factors, some of which cause people to have a life-threatening illness while others do not.
The results, published in the NEJM, explain the combination of the results of Covid 19 in two regions of the human genome based on genetic evidence from patients in China, Europe and the United States. But, in order to know the difference between the causes of the disease, scientists need to understand the role of proteins carried by the genome in the context of the disease.
A genomic “hotspot” linked to the severity of COVID-19 disease was found in a database compiled by Gerston and colleagues of all proteins and metabolites from different regions of the human genome. It took researchers a step further to understand that the same region that was linked to the protein has recently been caught in the process of infecting human cells with the SARS-CO2 virus.
“We are committed to maximizing the expression of high-protein proteins in the region that have been shown to be co-receptors for the virus that causes COVID-19. Targets proteins The work reveals which proteins in the human body are associated with SARS-CO2 and other viruses.
The second region, according to the report, was linked to a defective protein that appears to play a role in attracting immune cells called lymphocytes to infected areas. the study It also suggests that they may differ in genetic variants and protein races. Overall, these findings are important contributions to science in understanding the mysteries of COVID-19.

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