Taste bud cells cannot be targets of Kovid-19

Taste bud cells cannot be targets of Kovid-19

Let’s Start this Interesting Article Shared on DesiNew.xyz

New York: Contrary to previous findings stating that the novel coronovirus directly targets bud cells in Kovid-19 patients, a new study has now revealed that the sense of smell and taste associated with inflammation is due to infection loss.
“An intriguing initial symptom among some Kovid-19 patients is the loss of smell and sense of taste, causing suspicion that the virus that causes the disease, SARS-CoV-2, may target taste buds,” he said. said. Authors study at the University of Georgia in the US.
In a paper published in the journal ACS Pharmacology and Translation Science, the authors wrote, “But early data from mice suggest that this may not happen.”
According to study, Viruses cause infections by attacking and reproducing specific cells in the body, often damaging those cells or killing them in the process.
Research has shown that SARS-CoV-2 enters human cells via angiotensin-altered enzyme 2 (ACE2), a receptor on the surface of some cells, including the human tongue.
For the current findings, the research team wanted to find out if ACE2 was specifically expressed in taste bud cells, as well as when this receptor first emerges on tongue cells during embryonic development, a model given to mice By studying as an organism.
Although the mouse version of ACE2 is not susceptible to SARS-CoV-2, it has been expressed in mice in studies, which may clarify when people become infected and lose their sense of taste.
By analyzing data from oral cells of adult mice, the researchers found that ACE2 was rich in cells that give the tongue its rough surface, but cannot be found in most taste bud cells.
This means that the virus probably does not cause taste loss through direct infection of these cells, the researchers said.
Instead, taste buds may be damaged by inflammation due to infection.
The team also showed that other viruses that affect taste, including the flu virus, can affect different tongue cell types.
In addition, researchers analyzed data from oral cells of mice at three developmental stages and found ACE2 in neonatal mice but not in embryos.
Previous studies in humans that did not focus on oral cells suggest that ACE2 may be expressed at an early embryonic stage and then at a later stage.
Therefore, the team stated that different stages of the fetus may have different sensitivities to SARS-CoV-2 infection and more work needs to be done to determine the time and place of human ACE2 expression.

STAY TUNED WITH US FOR MORE INTERESTING CONTENT ONLY ON DESINEW.XYZ

Leave a Reply

Your email address will not be published. Required fields are marked *