There is no evidence to support Kovid-19 spreading from dogs to humans

There is no evidence to support Kovid-19 spreading from dogs to humans

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Researchers say a study that jumped from dogs to humans earlier this year, claiming coronauras (Kovid-19), is scientifically flawed, with no direct evidence to support its conclusion.
Researcher David Pollak of the University of Colorado, USA, said, “During this time of Kovid-19, we are seeing people publishing things that illuminate findings that leap wild on the basis of evidence and It’s not even one of them. ” .
For the current study, published in the journal Molecular Biology and Evolution, the research team looked at an April 2020 study by Zhuhua Xia of the University of Ottawa, Canada, which proposed that stray dogs may be the origin of the epidemic.
Many scientific novels are interested in the origins of coronaviruses. They want to know from which animal the SARS-CoV-2 virus responsible for Kovid-19 came before it jumped into humans.
According to the researchers, the classic way to address this is to find viruses with similar genome sequences in a particular animal host.
Xia, however, focuses on a feature of the coronovirus genome known as CpG content and found that a distal dog coronavirus had the same CpG content as SARS-CoV-2.
Because this distant virus replicated well in the dog’s digestive system, they concluded that the dog’s intestines were an ideal location to influence the CpG content of the parental SARS-CoV-2.
“However, there is no evidence for the logical basis of Xia’s argument, noting that all mammals have digestive systems,” the researchers wrote.
They showed that dogs are not specialized in their content of ZAP and ABOBEC3G proteins, which help protect humans from viruses and may interact with viral CpG content.
Scientists wrote, “More recently, a recent inoculation study found that other domestic mammalian hosts are susceptible to SARS-COV-2, show low sensitivity to canine, and no traces of viral RNA were detected.”
The current research team stated that although the recent origin of SARS-CoV-2 is uncertain, the best current evidence suggests the possibility that it was passed on to humans by horseshoe or possibly pangolin, a type in China Spiny is antique.
There is strong evidence that the virus has recently jumped between humans and these animals or other intermediate hosts.
The author stated that bat and pangolin viruses also have the same CpG content as human SARS-CoV-2, so the environment affected by viral CpG may have occurred much earlier and probably in one of these two mammals.
The dogs have not been justified by the recent available evidence of ancestors of SARS-CoV-2, the researchers concluded.


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