Treatment of Kovid-19 may increase antimicrobial resistance

Treatment of Kovid-19 may increase antimicrobial resistance

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Washington: The use of antibiotics in people with Kovid-19 may increase resistance to the benefits of drugs among a wider population, a new study suggests.
As a result of the virus, hospitalized patients are being given a combination of drugs to prevent possible secondary bacterial infections.
However, research from the University of Plymouth and Royal Cornwall Hospital Trust suggests that their increased use during epidemics may place an additional burden on wastewater treatment operations.
Writing in the Journal of Antimicrobial Chemotherapy, scientists say this may increase the level of antibiotics within the UK’s rivers or coastal waters, resulting in an increase in antimicrobial resistance (AMR), where bacteria are exposed to the action of antibiotics. Are resistant to .
This would be particularly acute in obtaining water from wastewater treatment operations working in large hospitals, or emergency ‘nightingale’ hospitals, where Kovid-19 has a concentration of patients.
The findings are based on reports that up to 95 percent of Kovid-19 inpatients are being prescribed antibiotics as part of their treatment, and there is concern that widespread environmental administration of drug administration on such a large scale There may be effects.
“Kovid-19 has influence in almost every aspect of our lives. But it study Its legacy can be felt long after the current epidemic is brought under control. From our previous research, we know that significant amounts of commonly prescribed drugs pass into treatment functions and our water courses, ”said Sean Comber, a professor of environmental chemistry at Plymouth and the lead author of the article.
“By developing a greater understanding of their effects, we can potentially inform future decisions about how to make decisions not only during epidemics, but also in place of emergency hospitals and comprehensive pharmaceutical and waste management,” Coomber said.
The Kovid-19 guidance issued by the National Institute for Health and Care Excellence (NICE) suggests that patients with Kovid-19 should be treated with doxycycline and either amoxicillin or a combination of other drugs, if bacterial infection Antibiotics if suspected, but withholding or stopping a bacterial infection is unlikely.
“With other hospitalized patients in the UK, and other countries, most of our patients with Kovid symptoms were prescribed antibiotics because it is very difficult to know whether a patient presenting with Kovid symptoms has a bacterial infection. “Said Powell, Consultant Pharmacist at Neil Royal Cornwall Hospital.
Pavel said, “We did a lot of work to try and identify patients who were unlikely to have bacterial infections, our patients were complaining of viral kovid infection in an effort to reduce the risk of antibiotics and The resulting environment “.
This research establishes patient numbers for emergency hospitals in the UK with temporary wastewater treatment capacity and available river water dilution emergency hospitals and allied towns across the country.
Using environmental impact data and modeling tools developed by the UK water industry, it provided treatment in an emergency hospital in the UK – Harrogate, ready to treat around 500 people – and was shown to reduce the risks posed by doxycycline, Assuming that the hospital was at full capacity.
“This is a comprehensive environmental safety assessment, which addresses potential risks to fish populations and the foods they depend on. Amoxicillin data indicated that fish populations and other wildlife are at risk.” There was little risk of direct impacts, but there is a potential environment. Concern for the selection of AMR if there is a 100 percent potential is “Tom Hutchinson, professor of environment and health at the university and a co-author on research.”
Amoxicillin is used to treat everything from pneumonia and throat infections to skin and ear infections.
“Antibiotics underlie all modern medicine, but AMR is an issue that may affect millions of people over the coming decades. Currently, the Kovid-19 pandemic is causing immense pain and loss of life worldwide. , But AMR has been – and will remain – one of the most significant threats to global human health, ”said Matthew Upton, a professor of medical microbiology at the university and a co-author on research.
“We handled it study So that we can begin to understand the widespread impact of the global epidemic on human health. It is clear that mass prescribing of antibiotics will increase levels in the environment and we know that it can select for resistant bacteria. Such studies are necessary so that we can plan to direct antibiotic prescriptions in future epidemics, ”said Upton.


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