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Vitamin D levels in the blood can predict future health risks, death: study

WASHINGTON: Free circulating vitamin D levels in the blood can help older men understand and predict future health risks, according to a recent study.
This suggests that the free, pre-existing condition of vitamin D circulating in the bloodstream is a more accurate predictor of future health and disease risk, as vitamin D deficiency is associated with more than one serious health condition. As we get older. , This study shows that further investigation into vitamin D levels and their link to poor health leads to further research. Can be a promising area.
Vitamin D deficiency is common in Europe, especially in the elderly. It is associated with a higher risk of developing many aging diseases such as heart disease, cancer and osteoporosis.
However, there are several forms of vitamin D, or metabolites, in the body, but these are the total amount of metabolites that are most often used to assess the status of vitamin D.
Prohormon converts 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D, which is considered to be the active form of vitamin D in our body. More than 99% of all vitamin D metabolites in our blood are protein bound, so only a small portion is free to remain biologically active. Therefore, free, active forms can be a better predictor of current and future health.
Dr. Lane Antonio of the University Hospitals Lyon in Belgium and a team of colleagues investigated whether the free metabolites of vitamin D predict better health, which affected 1,970 communities aged 40-79. Collected from living men. , Between 2003 and 2005. Levels of total and free metabolites of vitamin D were compared to their current health status, adjusting for potentially complex factors, including age, body mass index, smoking, and self-reported health. Total levels of both free and binding vitamin D metabolites were associated with an increased risk of death.
However, only 25-hydroxyvitamin D predicted future health problems and 1,25-hydroxyvitamin D was not free.
“These data further confirm that vitamin D deficiency is associated with a negative impact on general health and a higher risk of death can be predicted,” explains Dr. Antonio.
Since this is an observational study, the causes and relationships and the basic mechanisms are not determined. The study also failed to provide specific information on the causes of men’s deaths, which could be a confusing factor.
“Most studies focus on total 25-hydroxyvitamin D levels and the association between age-related disease and mortality. Since our body has an active form of 1,25-dihydroxyvitamin D, it was possible that This could be a strong predictor of disease and mortality. It is also debated whether total or free vitamin D levels should be measured. Our data show that total and free 25-hydro Oxytocin vitamin D levels are a good measure of future health risk in men.
Dr. Antonio and his team are currently finalizing the data analysis and writing a manuscript on the findings.


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