What you need to know about the J&J vaccine

What you need to know about the J&J vaccine

WASHINGTON (Reuters) – Johnson & Johnson’s only food, the Covid 19 pill, is expected to be adopted by the European Union on Thursday, the fourth block vaccine in the fight to end the epidemic.
Here’s what you need to know.
Probably the most important person to know is “Zero”.
Quad – How many people have died after being shot in a massive global trial of 19,000 to 40,000 people, compared to the seven who have won a placebo.
Overall, 28 days after the pill, the vaccine prevented moderate-to-severe Covid 19 by 66.1%, but considering the serious illness alone, it rose to 85.4%.
Most surprisingly, both South Africa and Brazil had good results against severe disease, with a variety of cases prevailing during the trial period.
In terms of safety, an analysis of 44,000 people showed that it is generally well tolerated, such as side effects such as pain at the injection site, headache, fatigue and muscle aches.
At least one case of anaphylaxis (severe allergic reaction) has been reported – and similar reactions have been reported in rare cases for other Covid 19 vaccines.
Documents shared by the U.S. Food and Drug Administration, which has already given emergency clearance to the shot, show a number of cases where vaccinators developed hives.
The FDA also said that long-term monitoring is needed to determine if the vaccine is linked to a number of potentially dangerous clotting cases, and tinnitus.
Vaccines based on Pfizer and modern RNA showed an efficacy of about 95% compared to all forms of Covid 19 – but it is still difficult to compare directly.
This is because their clinical trials preceded the new strains, some of which have been found to be less risky than existing vaccines, which are well established.
RNA vaccines may still have edges, but the J&J vaccine brings significant logistical benefits to the table.
It requires only one shot and can be stored longer in the refrigerator instead of in the freezer – this is especially important for developing countries.
Although there has been an outbreak of influenza, it is doubtful that the way the vaccine is developed will reduce such reactions.
The J&J vaccine uses a common cold-causing adenovirus, which has been genetically modified to replicate a gene for a significant portion of the corona virus, without replicating it. کرسکے۔
This part is known as the “spike protein” and is what makes the virus stand out like its crown.
The vaccine provides instructions for this protein to form in human cells, and then our immune system develops antibodies against it, which prevents the virus from invading the cells.
In addition to antibodies, the vaccine also produces immune T cells, which kill the infected cells and help make more antibodies.
J&J’s shot is known as the “Adenovirus Vector Vaccine” and the company developed the first EU-approved Ebola vaccine using the same technology.
Oxford – AstraZeneca and Sputnik shots are both adenovirus vector vaccines.
They all use double-stranded DNA molecules to carry genetic instructions instead of the single-stranded RNA used by Pfizer and Modern.
DNA is more invasive, which is why these vaccines can be protected at warmer temperatures.
With clinical trials for children and pregnant women, Jammu and Kashmir is moving fast.
Although J&J’s vaccine is a single dose so far, the company is also examining the two-dose order to see if it gets a better response.
When it comes to boosters, however, RNA vaccines may be the opposite of adenovirus vaccines.
Some scientists have raised concerns that the immune system will recognize and attack the adenovirus, reducing the effectiveness of the second shot.
This can be especially important because manufacturers are working to develop a variety of specific vaccines. Let’s see, because adenovirus vaccine makers may need to find new vectors.

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